UPK1B and KIR2DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UPK1B	KIR2DL3
Description		uroplakin 1B	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Response To Bacterium Epithelial Cell Differentiation	Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
Interacting Genes		55 interacting genes: BCL2L13 BEST2 BNIP2 CD53 CD69 CD80 CERS4 CLDN7 DAGLA EDAR FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GPR161 GPR37L1 GPX8 IQCB1 ISLR2 ITGB2 KASH5 KCNJ6 KIR2DL3 KLRC1 LMNA MFF MS4A4A NEMP1 PDZK1IP1 PIK3IP1 PLPP4 RHCG SAR1A SDHAF4 SHISA4 SIT1 SLC10A2 SLC16A2 SLC35C2 SLC39A2 SPINT1 SSMEM1 STX1A SYT9 TMEM139 TMEM237 TMEM262 TMEM45B TMEM54 TMEM91 TMUB2 UPK3A VSIG1	64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5
Entrez ID		7348	3804
HPRD ID		03853	10383
Ensembl ID		ENSG00000114638	ENSG00000243772
Uniprot IDs		O75841	E3NZD8 P43628
PDB IDs			1B6U 6PAG
Enriched GO Terms of Interacting Partners?
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