PHLDA2 and OTUB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PHLDA2	OTUB2
Description		pleckstrin homology like domain family A member 2	OTU deubiquitinase, ubiquitin aldehyde binding 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane	Nucleus
	Molecular Function	Protein Binding Phosphatidylinositol Phosphate Binding	Thiol-dependent Deubiquitinase Protein Binding Ubiquitin Binding
	Biological Process	Placenta Development Apoptotic Process Animal Organ Morphogenesis Regulation Of Gene Expression Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Regulation Of Embryonic Development Regulation Of Spongiotrophoblast Cell Proliferation Regulation Of Glycogen Metabolic Process Regulation Of Growth Hormone Activity	Protein Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Histone H2A K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair
Pathways			Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Calcium levels ( 20705733) Malaria ( 31844061)	Aspartate aminotransferase levels ( 33547301)
Interacting Genes		6 interacting genes: FCHO1 HSP90AA1 OTUB2 SSX2 SSX2B TH	42 interacting genes: APP ARRDC3 CDIP1 CPSF6 DAZAP2 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 MKRN1 PHLDA2 PJA1 PLEKHB2 PMEPA1 RBCK1 REL RFFL RNF126 SIAH1 SPART TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28
Entrez ID		7262	78990
HPRD ID		03679	07620
Ensembl ID		ENSG00000181649	ENSG00000089723
Uniprot IDs		Q53GA4	Q96DC9
PDB IDs			1TFF 4FJV 5QIO 5QIP 5QIQ 5QIR 5QIS 5QIT 5QIU 5QIV 5QIW 5QIX 5QIY 5QIZ
Enriched GO Terms of Interacting Partners?
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