TRPC6 and ITPR3

  • Number of citations of the paper that reports this interaction (PubMedID 11290752)
  • 84
  • Data Source:
  • HPRD (in vitro)

TRPC6

ITPR3

Description transient receptor potential cation channel subfamily C member 6 inositol 1,4,5-trisphosphate receptor type 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429)
  • Daytime nap ( 33568662)
  • General risk tolerance (MTAG) ( 30643258)
  • Lung adenocarcinoma ( 28604730)
  • Menarche (age at onset) ( 25231870)
  • Monocyte count ( 32888494)
  • Plateletcrit ( 32888494)
  • Severity of nausea and vomiting of pregnancy ( 29563502)
  • White blood cell count ( 32888494)
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Asthma and attention deficit hyperactivity disorder ( 31619474)
  • Body mass index ( 26426971)
  • Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
  • Crohn's disease ( 23850713)
  • Educational attainment ( 23722424)
  • Hodgkin's lymphoma ( 30194254)
  • Multiple sclerosis and body mass index (pleiotropy) ( 26920376)
  • Obesity (extreme) ( 19553259)
  • Phosphorus levels ( 20558539)
  • Regular attendance at a gym or sports club ( 29970889)
  • Total carotid plaque area (excess vs minimal atherosclerosis) ( 32811377)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes 9 interacting genes: FYN ITPR3 MX1 ORAI1 RNF24 SRC TRPC3 TRPC7 TRPM2 18 interacting genes: AKT1 ANK1 BAP1 BECN1 CABP1 ITPR1 MTDH MTNR1A MTNR1B SIGMAR1 TRPC1 TRPC2 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPM2
Entrez ID 7225 3710
HPRD ID 04710 00926
Ensembl ID ENSG00000137672 ENSG00000096433
Uniprot IDs Q9Y210 A6H8K3 Q14573 Q59ES2
PDB IDs 5YX9 6UZ8 6UZA 7A6U 6DQJ 6DQN 6DQS 6DQV 6DQZ 6DR0 6DR2 6DRA 6DRC 6UQK
Enriched GO Terms of Interacting Partners?
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