TRHR and IER3IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRHR	IER3IP1
Description		thyrotropin releasing hormone receptor	immediate early response 3 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane
	Molecular Function	Thyrotropin-releasing Hormone Receptor Activity Protein Binding	Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway	Positive Regulation Of Extracellular Matrix Constituent Secretion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Brain Development Protein Transport Organ Growth Positive Regulation Of Protein Secretion Regulation Of Fibroblast Apoptotic Process
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Protirelin
Diseases
GWAS		Body mass (lean) ( 19268274) Daytime sleep phenotypes ( 27126917) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969)	Fruit consumption ( 32066663)
Interacting Genes		19 interacting genes: ARRB1 C1QL4 COMT EFNA5 FAM241B FXYD6-FXYD2 GJB2 IER3IP1 NIPAL4 PEDS1-UBE2V1 SLC39A2 SLC39A9 SLC41A1 TMEFF2 TMEM218 TMEM239 TRH UBE2J1 YIPF6	43 interacting genes: AIG1 C19orf18 CDIPT CERS2 CERS4 CSNK2B CST1 DPM3 EBP ELOVL4 ERMP1 FAM210B FCER1G GJB1 GOSR2 GPR42 HERPUD2 JAGN1 KCNA1 MOSPD3 PEX12 PIGP PLP1 POMK RGS2 SCN3B SLC30A4 TK1 TM4SF18 TMEM128 TMEM14A TMEM14B TMEM167A TMEM237 TMEM258 TMEM80 TMEM86B TMPPE TMX2 TRHR UBQLN1 YIPF4 ZFYVE27
Entrez ID		7201	51124
HPRD ID		11767	13727
Ensembl ID		ENSG00000174417	ENSG00000134049
Uniprot IDs		P34981	Q9Y5U9
PDB IDs
Enriched GO Terms of Interacting Partners?
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