TPM4 and JRK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TPM4	JRK
Description		tropomyosin 4	Jrk helix-turn-helix protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Podosome Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Focal Adhesion Membrane Cortical Cytoskeleton Extracellular Exosome	Cellular_component Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding	DNA Binding MRNA Binding Protein Binding
	Biological Process	Osteoblast Differentiation Muscle Contraction Actin Filament Organization	Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Striated Muscle Contraction Smooth Muscle Contraction RHOV GTPase cycle Signaling by ALK fusions and activated point mutants
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Longevity ( 33657282) Mean platelet volume ( 31080455 22139419 32888494 22423221 27863252) Platelet count ( 26805783 22139419 32888494 22423221 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252)	Urinary tract infection frequency ( 28928442)
Interacting Genes		14 interacting genes: DANCR JRK LNX1 NOD2 PACSIN1 PICK1 PRKACA RAB8A SMURF1 SNAPIN TCERG1 TPM1 TPM3 TRIP6	37 interacting genes: ALAS1 BYSL C2CD6 CCDC136 CCDC57 CDC37 CNKSR3 FAM161A FBXO17 GOLGA6L9 HSF2BP IFRD2 KDM1A KPNA6 LDOC1 LGALS14 LY6E MTUS2 PDZD4 PICK1 PRICKLE1 TFIP11 TPM4 TRIM23 TRIM41 TRIP10 TSGA10 TXK USP2 UTP14C ZBTB8A ZNF343 ZNF417 ZNF620 ZNF629 ZNF655 ZRANB1
Entrez ID		7171	8629
HPRD ID		11734	04442
Ensembl ID		ENSG00000167460	ENSG00000234616
Uniprot IDs		A0A5F9UN72 K7ENT6 P67936 V9HW56	O75564
PDB IDs
Enriched GO Terms of Interacting Partners?
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