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TPM4

Description tropomyosin 4
Image No pdb structure
GO Annotations Cellular Component
  • Stress Fiber
  • Podosome
  • Cytosol
  • Cytoskeleton
  • Muscle Thin Filament Tropomyosin
  • Actin Filament
  • Focal Adhesion
  • Membrane
  • Cortical Cytoskeleton
  • Extracellular Exosome
Molecular Function
  • Calcium Ion Binding
  • Protein Binding
  • Structural Constituent Of Muscle
  • Identical Protein Binding
  • Protein Homodimerization Activity
  • Protein Heterodimerization Activity
  • Actin Filament Binding
Biological Process
  • Osteoblast Differentiation
  • Muscle Contraction
  • Actin Filament Organization
Pathways
  • Striated Muscle Contraction
  • Smooth Muscle Contraction
  • RHOV GTPase cycle
  • Signaling by ALK fusions and activated point mutants
Drugs
  • Phenethyl Isothiocyanate
Diseases
GWAS
  • Longevity ( 33657282)
  • Mean platelet volume ( 31080455 22139419 32888494 22423221 27863252)
  • Platelet count ( 26805783 22139419 32888494 22423221 27863252)
  • Platelet distribution width ( 32888494 27863252)
  • Plateletcrit ( 32888494 27863252)
Interacting Genes 14 interacting genes: DANCR JRK LNX1 NOD2 PACSIN1 PICK1 PRKACA RAB8A SMURF1 SNAPIN TCERG1 TPM1 TPM3 TRIP6
Entrez ID 7171
HPRD ID 11734
Ensembl ID ENSG00000167460
Uniprot IDs A0A5F9UN72 K7ENT6 P67936 V9HW56
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025