TPD52L1 and PAK6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TPD52L1	PAK6
Description		TPD52 like 1	p21 (RAC1) activated kinase 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Perinuclear Region Of Cytoplasm	Fibrillar Center Nucleoplasm Cytoplasm Cytosol Cell Junction
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Protein Serine Kinase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of MAP Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Apoptotic Signaling Pathway	Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Learning Memory Locomotory Behavior Intracellular Signal Transduction Regulation Of MAPK Cascade Neuron Projection Arborization Neuron Projection Extension
Pathways		Golgi Associated Vesicle Biogenesis	Activation of RAC1 CDC42 GTPase cycle RAC1 GTPase cycle RHOD GTPase cycle RHOH GTPase cycle RHOV GTPase cycle
Drugs			Fostamatinib
Diseases
GWAS		Night sleep phenotypes ( 27126917)	Obesity-related traits ( 23251661) Schizophrenia ( 25056061 29483656) Weight gain in amisulpride-treated first-episode psychosis ( 32126890)
Interacting Genes		15 interacting genes: ABL2 DAPK1 EIF3J GPR135 HDAC1 MAL2 MAP3K5 PAK6 PBX3 TPD52 TPD52L2 TPD52L3 YAE1 YWHAB YWHAZ	28 interacting genes: APP AR CACNA1H CDC42 CDIN1 CDK1 DAPK1 DLL4 ESR1 FBXO7 GJD2 HSF2BP KNL1 LIMK1 LRRK1 MAPK14 MDM2 NEK6 PTPRD RAC1 RHOJ RHOV SEMA3B SNX2 SP3 SPG11 SUMO2 TPD52L1
Entrez ID		7164	56924
HPRD ID		07236	06426
Ensembl ID		ENSG00000111907	ENSG00000137843
Uniprot IDs		E9PNK6 E9PPQ1 J3KNE7 Q15730 Q16890	A0A024R9Q4 Q9NQU5
PDB IDs			2C30 2ODB 4KS7 4KS8 6QDR 6QDS
Enriched GO Terms of Interacting Partners?
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