TPD52 and SENP2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TPD52	SENP2
Description		tumor protein D52	SUMO specific peptidase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Nucleus Nuclear Pore Nucleoplasm Cytosol PML Body Nuclear Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity	Protein Binding SUMO-specific Protease Activity SUMO-specific Endopeptidase Activity
	Biological Process	Anatomical Structure Morphogenesis B Cell Differentiation Secretion	Protein Transport Wnt Signaling Pathway Protein Desumoylation Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Protein Destabilization Fat Cell Differentiation MRNA Transport
Pathways		Golgi Associated Vesicle Biogenesis	SUMO is proteolytically processed
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31361310 31959851 34103634 27182965 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Kawasaki disease ( 33772158) Lapatinib-induced hepatotoxicity ( 25987243) Metabolite levels (HVA/MHPG ratio) ( 23319000) Metabolite levels (Pyroglutamine) ( 23934736) Rheumatoid arthritis ( 30423114 24390342) Self-reported allergy ( 23817569)	Diastolic blood pressure ( 28135244 27841878) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163 31015462) Height ( 28552196) Hip circumference ( 28552196) JT interval ( 29874175) PR interval ( 30046033 32439900) QRS duration ( 30012220) Seborrheic dermatitis ( 29203360) Systolic blood pressure ( 27841878 26969751)
Interacting Genes		14 interacting genes: ANXA6 AR MAL2 SENP2 SH3GLB1 SOCS2 SPG21 SRPK2 STUB1 THAP4 TPD52L1 TPD52L2 TPD52L3 TTPA	39 interacting genes: ACSF2 AGTRAP APOC2 APOC4 APP ARL6IP1 ARMC12 AXIN1 CDCA5 CDK5RAP2 DAXX ERCC6 FUNDC1 FZR1 HCCS IKBKG KASH5 KPNA1 KPNB1 LMNA MYC NACC1 NEDD4L NUP153 OGT PML RANGAP1 RETREG3 RPRM SDR16C5 STK38 SUMO1 SUMO2 SUMO3 SYNE4 TMEM239 TNFRSF10D TPD52 TRIM63
Entrez ID		7163	59343
HPRD ID		04963	07002
Ensembl ID		ENSG00000076554	ENSG00000163904
Uniprot IDs		P55327	Q9HC62
PDB IDs			1TGZ 1TH0 2IO0 2IO1 2IO2 2IO3 3ZO5 5AEK
Enriched GO Terms of Interacting Partners?
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