TPD52 and THAP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TPD52	THAP4
Description		tumor protein D52	THAP domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Cellular_component
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity	DNA Binding Protein Binding Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding
	Biological Process	Anatomical Structure Morphogenesis B Cell Differentiation Secretion	Tyrosine Metabolic Process Nitrate Metabolic Process
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31361310 31959851 34103634 27182965 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Kawasaki disease ( 33772158) Lapatinib-induced hepatotoxicity ( 25987243) Metabolite levels (HVA/MHPG ratio) ( 23319000) Metabolite levels (Pyroglutamine) ( 23934736) Rheumatoid arthritis ( 30423114 24390342) Self-reported allergy ( 23817569)	Brain structure ( 20171287) Hip circumference adjusted for BMI ( 34021172) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		14 interacting genes: ANXA6 AR MAL2 SENP2 SH3GLB1 SOCS2 SPG21 SRPK2 STUB1 THAP4 TPD52L1 TPD52L2 TPD52L3 TTPA	42 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6
Entrez ID		7163	51078
HPRD ID		04963	11630
Ensembl ID		ENSG00000076554	ENSG00000176946
Uniprot IDs		P55327	Q8WY91
PDB IDs			3IA8
Enriched GO Terms of Interacting Partners?
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