Description |
DNA topoisomerase I |
cytoskeleton associated protein 5 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
- Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
- Brain morphology (MOSTest) ( 32665545)
- Cholesterol, total ( 24097068 20686565)
- Fasting glucose ( 33402679)
- Hemoglobin ( 32888494)
- Hip circumference adjusted for BMI ( 34021172)
- LDL cholesterol ( 24097068 20686565)
- LDL cholesterol levels ( 28334899)
- LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
- LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
- Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
- Male-pattern baldness ( 28196072)
- Metabolite levels ( 23823483)
- PR interval ( 32439900)
- Red blood cell count ( 32888494)
- Refractive error ( 32231278)
- Total cholesterol levels ( 28334899)
- Urate levels ( 31578528)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172)
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- Alzheimer's disease (late onset) ( 30820047)
- Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Immunoglobulin A ( 20694011)
- Pulse pressure ( 30578418)
- Schizophrenia ( 29483656)
- Serum metabolite levels ( 33031748)
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Interacting Genes |
61 interacting genes:
APAF1
APP
ATM
BARD1
BRCA1
BRD2
BTBD1
BTBD2
BUB3
CASP3
CASP6
CDK8
CKAP5
CSNK2A1
CSNK2A2
DDB2
ELK3
ERCC8
ERG
FSHR
GEMIN4
IL7R
IRF4
IRF8
IRF9
JAK1
JUN
KMT2A
LIG4
LSM4
MDM2
NCL
NCOA6
PDE10A
PIAS4
PPP2R2B
PRB1
PRKDC
PYGM
RBL1
RBL2
RCVRN
SF3B1
SFPQ
SNRNP70
SNW1
SRPK2
SRSF1
SRSF11
SUMO1
SYMPK
TARBP2
TDP1
TOPORS
TP53
TRIM32
TUBD1
U2AF2
UBE2I
XRCC5
XRCC6
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11 interacting genes:
ARHGEF16
AURKA
CACNA1A
CLASP1
CLK1
NDC80
PTPRN2
SLAIN2
SUMO2
TOP1
USP19
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Entrez ID |
7150 |
9793 |
HPRD ID |
00535 |
10830 |
Ensembl ID |
ENSG00000198900
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ENSG00000175216
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Uniprot IDs |
P11387
Q9BVT2
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Q14008
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PDB IDs |
1A31
1A35
1A36
1EJ9
1K4S
1K4T
1LPQ
1NH3
1R49
1RR8
1RRJ
1SC7
1SEU
1T8I
1TL8
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4QMI
4QMJ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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