ARMC8 and PKP1

Number of citations of the paper that reports this interaction (PubMedID 30482882)
3

Data Source:
BioGRID (two hybrid)

		ARMC8	PKP1
Description		armadillo repeat containing 8	plakophilin 1
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol GID Complex Specific Granule Lumen Intracellular Membrane-bounded Organelle Tertiary Granule Lumen	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Intermediate Filament Plasma Membrane Adherens Junction Desmosome Ficolin-1-rich Granule Membrane Messenger Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Protein Binding Lamin Binding Intermediate Filament Binding Structural Constituent Of Skin Epidermis Cadherin Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Cell-cell Junction Assembly Cell Adhesion Signal Transduction Positive Regulation Of Gene Expression Intermediate Filament Bundle Assembly Cell-cell Adhesion Negative Regulation Of MRNA Catabolic Process
Pathways		Neutrophil degranulation	Apoptotic cleavage of cell adhesion proteins Neutrophil degranulation Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Body shape index ( 34021172) Mean spheric corpuscular volume ( 32888494) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Panic disorder ( 19165232) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		11 interacting genes: CIB3 CTNNA1 GID8 MAEA PKP1 PKP2 PKP4 STX6 TCF12 TNNT1 ZMYND12	18 interacting genes: AP2B1 ARMC8 BICDL2 CARD10 CEP76 DSC1 DSG1 DSP GOLGA2 GTF2IRD1 HOOK2 HSF2BP KRT14 KRT8 NFKBID TNS2 UCHL5 VIM
Entrez ID		25852	5317
HPRD ID		09992	03579
Ensembl ID		ENSG00000114098	ENSG00000081277
Uniprot IDs		B7Z637 Q8IUR7	A0A024R952 Q13835
PDB IDs			1XM9
Enriched GO Terms of Interacting Partners?
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