TMSB4X and KRTAP8-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMSB4X	KRTAP8-1
Description		thymosin beta 4 X-linked	keratin associated protein 8-1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Platelet Alpha Granule Lumen	Cytosol Intermediate Filament
	Molecular Function	RNA Binding Actin Monomer Binding Protein Binding Enzyme Binding	Protein Binding
	Biological Process	Actin Filament Organization Cytoplasmic Sequestering Of NF-kappaB Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-8 Production Tumor Necrosis Factor-mediated Signaling Pathway Sequestering Of Actin Monomers Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Inflammatory Response Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of ATP Biosynthetic Process
Pathways		Platelet degranulation	Keratinization
Drugs
Diseases
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738)	Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		38 interacting genes: ACTA1 ACTA2 ACTB ACTG1 AKAP8L ALAS1 ANXA7 APLP1 CDKN1A COG6 FAM118B FHL3 GOLGA6L9 GRB7 HSF2BP IGSF21 ILK KRT13 KRT15 KRT31 KRT34 KRT36 KRT40 KRTAP8-1 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6 UHMK1	78 interacting genes: AANAT AGXT AOC1 ARID5A ATG9A ATXN1L BANP BCAS2 BHLHE40 C11orf16 C1orf94 C20orf85 CAMK2A CCDC17 CCNK CDA CERCAM CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRTB1 DTX2 FAAP20 FAM168A FAM83A FOXD2 FOXP3 GATA2 GCM2 GLIS2 HEY2 HOXC8 HYPK KRTAP12-4 KRTAP19-5 KRTAP26-1 MFSD13A MKRN3 MYOZ3 NKX2-5 NOXA1 P4HA3 PAX3 PITX1 PLSCR4 POGZ POU6F2 PPP1R32 PROP1 PRR13 PRR35 PSMA3 RAMAC RBPMS RBPMS2 RNF38 RUSC1 SMR3A SMUG1 SNRPC TBX18 TEKT3 TIAL1 TLE5 TLX3 TMSB4X TNIP1 TNPO2 TSPYL6 VENTX VEZF1 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZNF34
Entrez ID		7114	337879
HPRD ID		02153	11221
Ensembl ID		ENSG00000205542	ENSG00000183640
Uniprot IDs		A2VCK8 P62328 Q0P5T0	Q8IUC2
PDB IDs		1UY5 3TU5 4PL7 4PL8
Enriched GO Terms of Interacting Partners?
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