TMPO and LMNB1

Number of citations of the paper that reports this interaction (PubMedID 9490046)
8

Data Source:
HPRD (in vitro, two hybrid)

		TMPO	LMNB1
Description		thymopoietin	lamin B1
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nuclear Envelope	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Cytosol Membrane Nuclear Matrix Nuclear Membrane
	Molecular Function	DNA Binding Protein Binding Lamin Binding Cadherin Binding	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process
Pathways		RHOA GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle	Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation RHOD GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)
Interacting Genes		24 interacting genes: ABL1 AKAP8L BANF1 CLK1 CSNK2A1 FXR1 GMCL1 GOLM1 HDAC3 KLHL6 LMNA LMNB1 LMNB2 OGT OIP5 RB1 RNF123 SGTA SGTB SRC SRPK2 STOM SUMO2 USP7	42 interacting genes: ABCG8 ATF4 CASP3 CASP6 CCDC88B CDK1 CENPH DMAP1 FAM169A GABARAP GIT2 GZMA GZMB KPNA5 KPNA6 LBR LMNA M1AP MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PIH1D2 PLEC PPP1R13B PRKCA PRKCB PRKCD PRPH PTEN RNF123 SERPINA3 SNAPIN SRPK2 SUMO4 TMPO TOR1AIP1 TP53BP2 UBE2I URB2 YWHAQ
Entrez ID		7112	4001
HPRD ID		01777	01036
Ensembl ID		ENSG00000120802	ENSG00000113368
Uniprot IDs		A0A024RBE7 A0A024RBH7 G5E972 P42166 P42167 Q59G12	B4DZT3 P20700
PDB IDs		1GJJ 1H9E 1H9F	2KPW 3JT0 3TYY 3UMN 5VVX
Enriched GO Terms of Interacting Partners?
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