TLL2 and DNTT

		TLL2	DNTT
Description		tolloid like 2	DNA nucleotidylexotransferase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Euchromatin Nucleus Nucleoplasm Cytosol Nuclear Matrix
	Molecular Function	Metalloendopeptidase Activity Serine-type Endopeptidase Activity Calcium Ion Binding Zinc Ion Binding	DNA Binding DNA-directed DNA Polymerase Activity DNA Nucleotidylexotransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Proteolysis Cell Differentiation Collagen Fibril Organization Negative Regulation Of Skeletal Muscle Tissue Growth	DNA Metabolic Process Double-strand Break Repair Via Nonhomologous End Joining DNA Modification Response To ATP DNA Biosynthetic Process
Pathways		Degradation of the extracellular matrix Collagen biosynthesis and modifying enzymes Anchoring fibril formation Crosslinking of collagen fibrils
Drugs		Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy)phosphoryl}-L-alanyl-L-prolinate	2',3'-Dideoxyadenosine triphosphate
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Platelet reactivity in response to clopidogrel treatment ( 32472697) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)
Interacting Genes		5 interacting genes: DNTT HPSE2 PAPSS2 PPP1R3C RBP4	10 interacting genes: ABTB2 DNTTIP1 DNTTIP2 MEI4 PCNA PRPF19 REL TCF4 TLL2 XRCC6
Entrez ID		7093	1791
HPRD ID		05993	08925
Ensembl ID		ENSG00000095587	ENSG00000107447
Uniprot IDs		Q9Y6L7	P04053
PDB IDs			2COE 5W4E
Enriched GO Terms of Interacting Partners?
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