TFAM and MGST3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TFAM	MGST3
Description		transcription factor A, mitochondrial	microsomal glutathione S-transferase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Protein-containing Complex Mitochondrial Nucleoid	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Cis-regulatory Region Binding Mitochondrial Promoter Sequence-specific DNA Binding Transcription Coactivator Binding Chromatin Binding RNA Binding Protein Binding DNA Binding, Bending Heat Shock Protein Binding Mitochondrial Transcription Factor Activity Sequence-specific DNA Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding
	Biological Process	Mitochondrial Transcription Transcription Initiation From Mitochondrial Promoter Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Transcription, DNA-templated	Lipid Metabolic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Cellular Oxidant Detoxification
Pathways		Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis	Glutathione conjugation Aflatoxin activation and detoxification
Drugs			Glutathione
Diseases
GWAS		Blood urea nitrogen levels ( 29403010) Height ( 23456168) Metabolite levels ( 23823483) Midgestational circulating levels of PCBs ( 28235828) Mitochondrial heteroplasmy measurement ( 33731350) Refractive error ( 32231278)	Metabolite levels ( 23823483) Total ventricular volume ( 21116278)
Interacting Genes		10 interacting genes: AGTRAP ARL6IP1 COL8A2 MGST3 PNP STATH TECR TFB1M TFB2M TSPAN1	88 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FCGR2A FCGR2B FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1
Entrez ID		7019	4259
HPRD ID		02702	05192
Ensembl ID		ENSG00000108064	ENSG00000143198
Uniprot IDs		E5KSU5 Q00059	A0A024R8Z1 O14880
PDB IDs		3FGH 3TMM 3TQ6 4NNU 4NOD 6ERP 6ERQ 6HB4 6HC3
Enriched GO Terms of Interacting Partners?
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