MGST3 and CACNG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MGST3	CACNG1
Description		microsomal glutathione S-transferase 3	calcium voltage-gated channel auxiliary subunit gamma 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Integral Component Of Plasma Membrane T-tubule Sarcolemma L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding
	Biological Process	Lipid Metabolic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Cellular Oxidant Detoxification	Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
Pathways		Glutathione conjugation Aflatoxin activation and detoxification
Drugs		Glutathione	Ergocalciferol Enflurane Ibutilide Diltiazem Spironolactone Lercanidipine Ethanol Fluspirilene Butamben Bioallethrin
Diseases
GWAS		Metabolite levels ( 23823483) Total ventricular volume ( 21116278)	Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		88 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FCGR2A FCGR2B FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1	13 interacting genes: CPLX4 FFAR2 GAD2 GPX8 HSD17B13 LMNA MGST3 MUC1 ODF4 THAP4 TLCD4 TMEM45B VAPA
Entrez ID		4259	786
HPRD ID		05192	00249
Ensembl ID		ENSG00000143198	ENSG00000108878
Uniprot IDs		A0A024R8Z1 O14880	Q06432
PDB IDs
Enriched GO Terms of Interacting Partners?
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