TEAD1 and GCAT

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TEAD1	GCAT
Description		TEA domain transcription factor 1	glycine C-acetyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex TEAD-YAP Complex	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Glycine C-acetyltransferase Activity Pyridoxal Phosphate Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Protein-containing Complex Assembly Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II	Cellular Amino Acid Metabolic Process Biosynthetic Process L-threonine Catabolic Process To Glycine
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination	Threonine catabolism
Drugs			Pyridoxal phosphate Glycine
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Central retinal vein equivalent ( 26567291) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diisocyanate-induced asthma ( 25918132) Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels x loop diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103) Hip circumference adjusted for BMI ( 34021172) HOMA-B (corrected for HOMA-IR) ( 30369944) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil count ( 32888494) Rheumatic heart disease ( 34106200)	Brain morphology (MOSTest) ( 32665545) Mean corpuscular volume ( 32888494)
Interacting Genes		21 interacting genes: BORCS8-MEF2B ENO1 GCAT HLA-DMB INSR MAX MEF2A MEF2C MYH7 NCOA1 SRF TBP TRIM3 UBTD1 VGLL1 VGLL2 VGLL3 VGLL4 WWTR1 YAP1 ZDHHC17	3 interacting genes: MDM2 TDH TEAD1
Entrez ID		7003	23464
HPRD ID		01802	07602
Ensembl ID		ENSG00000187079	ENSG00000100116
Uniprot IDs		P28347 Q59EF3	A8K228 O75600
PDB IDs		2HZD 3KYS 4RE1 4Z8E 5NNX 6HIL 6IM5 7CMM
Enriched GO Terms of Interacting Partners?
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