DYNLT3 and CYBB

		DYNLT3	CYBB
Description		dynein light chain Tctex-type 3	cytochrome b-245 beta chain
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Cytoplasm Cytoplasmic Dynein Complex Mitotic Spindle Astral Microtubule	Nuclear Envelope Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Dendrite Phagocytic Vesicle Membrane Specific Granule Membrane NADPH Oxidase Complex Neuronal Cell Body Tertiary Granule Membrane Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding	Voltage-gated Ion Channel Activity Protein Binding Electron Transfer Activity Superoxide-generating NAD(P)H Oxidase Activity Heme Binding Metal Ion Binding Protein Heterodimerization Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Microtubule-based Movement Cell Cycle Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Cell Division	Superoxide Metabolic Process Defense Response Inflammatory Response Response To Nutrient Response To Xenobiotic Stimulus Electron Transport Chain Positive Regulation Of Tumor Necrosis Factor Production Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Superoxide Anion Generation Innate Immune Response Respiratory Burst Positive Regulation Of Angiogenesis Cellular Response To Cadmium Ion Cellular Response To Ethanol Hypoxia-inducible Factor-1alpha Signaling Pathway Response To Aldosterone Cellular Response To L-glutamine Response To Angiotensin
Pathways			ROS and RNS production in phagocytes Cross-presentation of particulate exogenous antigens (phagosomes) Detoxification of Reactive Oxygen Species VEGFA-VEGFR2 Pathway RHO GTPases Activate NADPH Oxidases Neutrophil degranulation RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle
Drugs			Dextromethorphan
Diseases
GWAS
Interacting Genes		16 interacting genes: C2orf15 CCL28 CD5 CYBB DYNC1I1 DYNC1I2 DYNLT1 FOS IFITM1 NIF3L1 PMS1 PVR TESC UIMC1 VDAC1 ZC3H14	8 interacting genes: ACTG1 CYBA CYBC1 DYNLT3 IQGAP1 NCF2 NCF4 RAC1
Entrez ID		6990	1536
HPRD ID		02249	02382
Ensembl ID		ENSG00000165169	ENSG00000165168
Uniprot IDs		P51808	A0A0S2Z3S6 P04839
PDB IDs			3A1F
Enriched GO Terms of Interacting Partners?
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