TCP10L3 and PARD6A

Number of citations of the paper that reports this interaction (PubMedID 10934474)
321

Data Source:
HPRD (two hybrid)

		TCP10L3	PARD6A
Description		t-complex 10 like 3, pseudogene	par-6 family cell polarity regulator alpha
Image		No pdb structure
GO Annotations	Cellular Component		Ruffle Nucleus Centrosome Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Centriolar Satellite
	Molecular Function		Protein Kinase C Binding Protein Binding Transcription Factor Binding GTP-dependent Protein Binding Small GTPase Binding
	Biological Process		Negative Regulation Of Protein Phosphorylation Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Viral Process Cell-cell Junction Maintenance Positive Regulation Of Protein Secretion Cell Division Regulation Of Cellular Localization Positive Regulation Of Protein Localization To Centrosome
Pathways			TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Tight junction interactions Asymmetric localization of PCP proteins CDC42 GTPase cycle RAC1 GTPase cycle RHOU GTPase cycle RHOV GTPase cycle
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		6 interacting genes: APP CEP43 FBXO7 PARD6A PARD6B UBC	27 interacting genes: APP ATP5MG CDC42 CDH5 CRB3 DVL2 ECT2 GLS MAP2K5 MARK2 MARK4 PARD3 PARD6B PLCB1 PLCB3 PRKCG PRKCH PRKCI PRKCZ PTPN21 RAC1 RHOQ TCP10L3 TGFBR1 WDR83 YWHAH YWHAZ
Entrez ID		6953	50855
HPRD ID		01752	06316
Ensembl ID		ENSG00000203690	ENSG00000102981
Uniprot IDs			Q9NPB6
PDB IDs			1WMH
Enriched GO Terms of Interacting Partners?
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