PARD6A and ATP5MG

		PARD6A	ATP5MG
Description		par-6 family cell polarity regulator alpha	ATP synthase membrane subunit g
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleus Centrosome Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Centriolar Satellite	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex
	Molecular Function	Protein Kinase C Binding Protein Binding Transcription Factor Binding GTP-dependent Protein Binding Small GTPase Binding	Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Negative Regulation Of Protein Phosphorylation Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Viral Process Cell-cell Junction Maintenance Positive Regulation Of Protein Secretion Cell Division Regulation Of Cellular Localization Positive Regulation Of Protein Localization To Centrosome	ATP Synthesis Coupled Proton Transport Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Tight junction interactions Asymmetric localization of PCP proteins CDC42 GTPase cycle RAC1 GTPase cycle RHOU GTPase cycle RHOV GTPase cycle	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs			Artenimol Phenethyl Isothiocyanate
Diseases
GWAS		Obesity-related traits ( 23251661) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		27 interacting genes: APP ATP5MG CDC42 CDH5 CRB3 DVL2 ECT2 GLS MAP2K5 MARK2 MARK4 PARD3 PARD6B PLCB1 PLCB3 PRKCG PRKCH PRKCI PRKCZ PTPN21 RAC1 RHOQ TCP10L3 TGFBR1 WDR83 YWHAH YWHAZ	11 interacting genes: C2CD2L CEP164 GCKR MAGEC1 PARD6A PLEKHA4 PPP1CA RHOU SIK3 SLC4A1AP SRD5A2
Entrez ID		50855	10632
HPRD ID		06316	09815
Ensembl ID		ENSG00000102981	ENSG00000167283
Uniprot IDs		Q9NPB6	O75964
PDB IDs		1WMH
Enriched GO Terms of Interacting Partners?
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