GCFC2 and CREB3L2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GCFC2	CREB3L2
Description		GC-rich sequence DNA-binding factor 2	cAMP responsive element binding protein 3 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol U2-type Post-mRNA Release Spliceosomal Complex	Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Endoplasmic Reticulum
	Molecular Function	DNA Binding Protein Binding	Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific CAMP Response Element Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated	Chondrocyte Differentiation Regulation Of Transcription By RNA Polymerase II Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Response To Wounding Positive Regulation Of Gene Expression Positive Regulation Of Neuron Projection Development Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cartilage Development
Pathways		mRNA Splicing - Major Pathway	CREB3 factors activate genes
Drugs
Diseases
GWAS		Chronotype ( 30696823) Depression in multiple sclerosis (post-diagnosis) ( 33296963) Hippocampal atrophy ( 22745009)	Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Monocyte count ( 32888494) Pulse pressure ( 27841878) Refractive error ( 32231278) Total cholesterol levels ( 31217584) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		3 interacting genes: ATXN1 CREB3L2 TFIP11	10 interacting genes: CEP19 GABARAPL1 GAS7 GCFC2 GULP1 PTP4A1 PXN RGS16 RND1 ZNF212
Entrez ID		6936	64764
HPRD ID		01791	16391
Ensembl ID		ENSG00000005436	ENSG00000182158
Uniprot IDs		A4UHR0 B3KUM5 P16383 Q9BVX3	Q68D60 Q70SY1
PDB IDs
Enriched GO Terms of Interacting Partners?
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