TAP2 and PSMG3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TAP2	PSMG3
Description		transporter 2, ATP binding cassette subfamily B member	proteasome assembly chaperone 3
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Speck Integral Component Of Endoplasmic Reticulum Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane MHC Class I Peptide Loading Complex TAP Complex	Protein-containing Complex
	Molecular Function	Protein Binding ATP Binding ABC-type Peptide Antigen Transporter Activity ABC-type Peptide Transporter Activity MHC Class Ib Protein Binding MHC Class I Protein Binding Peptide Antigen Binding ATPase-coupled Transmembrane Transporter Activity Metal Ion Binding TAP1 Binding Tapasin Binding Peptide Transmembrane Transporter Activity	Protein Binding Protein-containing Complex Binding Molecular Adaptor Activity
	Biological Process	Adaptive Immune Response Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Via ER Pathway, TAP-dependent Protein Transport Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Cytosol To Endoplasmic Reticulum Transport Peptide Antigen Transport Transmembrane Transport	Proteasome Assembly Chaperone-mediated Protein Complex Assembly
Pathways		ER-Phagosome pathway ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma and major depressive disorder ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Composite immunoglobulin trait (IgA/IgG) ( 28628107) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) IgA nephropathy ( 25305756) Lymphocyte counts ( 32888494) Lymphoma ( 23349640) Nephropathy ( 21399633) Platelet distribution width ( 32888494) Pubertal anthropometrics ( 23449627) Response to hepatitis B vaccine ( 29534301) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Type 1 diabetes (age at diagnosis) ( 33179336) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Urate levels in lean individuals ( 25811787) Waist circumference adjusted for body mass index ( 34021172)	Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder ( 28416812) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		9 interacting genes: APP HLA-C HLA-G PSMB5 PSMB8 PSMG3 RBM18 TAP1 TAPBP	6 interacting genes: PSMB1 PSMB3 PSMB4 PSMB5 PSMG4 TAP2
Entrez ID		6891	84262
HPRD ID		01360	14404
Ensembl ID		ENSG00000204267	ENSG00000157778
Uniprot IDs		Q03519 Q5JNW1 Q9UP03 X5CMH5	A0A024R806 Q9BT73
PDB IDs		5U1D	2Z5E 6JPT
Enriched GO Terms of Interacting Partners?
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