Description |
serine/threonine kinase 11 |
cyclin dependent kinase inhibitor 2B |
Image |
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No pdb structure |
GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Asthma (childhood onset) ( 31036433)
- Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
- Crohn's disease ( 28067908)
- Distal/Left-sided colorectal cancer ( 33632709)
- Inflammatory bowel disease ( 28067908)
- Lymphocyte counts ( 32888494 27863252)
- Lymphocyte percentage of white cells ( 32888494)
- Neutrophil percentage of white cells ( 32888494)
- PR interval ( 32439900)
- Psychosis in Alzheimer's disease ( 22005930)
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Interacting Genes |
140 interacting genes:
ABCB5
ADIPOR1
AKT1
ALDOB
ANP32B
APP
ARAF
ARG2
ARNT
ATM
AURKA
BAP1
BCAS3
BECN1
BRAF
CAB39
CALM2
CBLC
CCDC180
CCND2
CCNE1
CD44
CDC14B
CDC37
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
CFL2
CRY2
CTSB
CYLC2
CYP17A1
D2HGDH
DACH1
EEF1A2
EPHA2
ERBB2
ERLEC1
ETV4
FAIM2
FAM98B
FBP1
FBP2
FGFR4
FZR1
GLIS2
GNPDA1
GRM1
HERC2
HGF
HIF1A
HRAS
IGFBP3
KAT2A
KDELR2
KLK7
LATS2
LEF1
LYPD3
MADCAM1
MAP2K1
MAP2K3
MAP2K5
MAP2K6
MAP3K5
MAPK14
MAPK3
MAPRE1
MARK1
MARK2
MARK4
MDM2
MET
MOB4
MOCS2
MT-ND2
MYC
NANS
NAT2
NF2
PARD3
PDGFRA
PDXP
PHF23
PIK3CA
PLD3
PPP2CB
PPP6R1
PRKAA1
PRKAA2
PRKACA
PRSS50
PTEN
RASA1
RASSF1
RHOBTB2
RPS6KA3
RPS6KA5
RPS6KB1
S100A14
SEPTIN9
SERPINB5
SH3GL1
SIK1
SIRT1
SMAD1
SMARCA4
SNRK
SOX4
SPDEF
ST14
STK11IP
STK24
STRADA
STRADB
STX17
TBC1D23
TDRD7
TEAD2
TERT
THOP1
THRSP
TNFRSF1A
TNIP2
TP53
TRIM25
TRMO
TSG101
TUBA1A
TUBB4A
UBE2D2
VPS72
WT1
XPA
YWHAG
ZNF189
ZNF195
ZNF510
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65 interacting genes:
AKT1
APP
ARAF
ARNT
ARPC3
ATP6V1H
BECN1
CBLC
CCDC33
CCDC90B
CCNC
CCND2
CCNE1
CD44
CDK17
CDK4
CDK6
CDK8
CDKN2A
CDKN2C
CEP126
CNKSR3
ELAVL2
ELP1
EPHA2
ERBB2
FGFR4
FZR1
GLIS2
GRM1
HGF
HIF1A
IGF1R
INCA1
ISL1
KAT2A
KDELR2
LATS2
MAGEA11
MAP2K3
MAP2K5
MAP2K6
MDM4
MET
MYC
NF2
NIF3L1
PDGFRA
PICK1
PYCR3
RAF1
RASSF1
RTL8C
RUSC1
SPG21
STK11
TEAD2
TERT
TGFB1I1
TNFRSF1A
TP53
TRAF1
TSC1
TTYH2
ZBTB17
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Entrez ID |
6794 |
1030 |
HPRD ID |
03740 |
02696 |
Ensembl ID |
ENSG00000118046
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ENSG00000147883
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Uniprot IDs |
A0A0S2Z4D1
Q15831
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K7PPU3
P42772
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PDB IDs |
2WTK
4ZDR
5WXN
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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