SNX2 and SNX32

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SNX2	SNX32
Description		sorting nexin 2	sorting nexin 32
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Protein-containing Complex	Endosome Cytosol
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding Phosphatidylinositol Binding
	Biological Process	Intracellular Protein Transport Endocytosis Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Lamellipodium Morphogenesis	Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308) Plateletcrit ( 32888494) Subcortical volume (MOSTest) ( 32665545)	Acne (severe) ( 24927181) Allergic sensitization ( 30013184) Birth weight ( 31043758) Breast cancer ( 23535729) Inflammatory bowel disease ( 23128233) Neutrophil count ( 32888494) Platelet count ( 32888494) Rosacea symptom severity ( 29771307) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: ACVR1B ACVR2B ARL6IP1 C1orf122 CENPQ CSNK2B DUSP10 EGFR FNBP1 INSR LAMC1 LEPR MET MTIF3 NFYC PAK6 PDGFRA PDGFRB PLIN3 PNKP SNX1 SNX32 SNX4 SNX5 SNX6 TMEM239 YIF1A ZNF202	11 interacting genes: C22orf39 EML2 GRXCR1 MNS1 NME7 SNX1 SNX2 SPANXB1 TEX11 TFIP11 TSG101
Entrez ID		6643	254122
HPRD ID		09332	08090
Ensembl ID		ENSG00000205302	ENSG00000172803
Uniprot IDs		O60749	Q86XE0
PDB IDs			6E8R
Enriched GO Terms of Interacting Partners?
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