SNX32 and SNX1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SNX32	SNX1
Description		sorting nexin 32	sorting nexin 1
Image
GO Annotations	Cellular Component	Endosome Cytosol	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Phosphatidylinositol Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Allergic sensitization ( 30013184) Birth weight ( 31043758) Breast cancer ( 23535729) Inflammatory bowel disease ( 23128233) Neutrophil count ( 32888494) Platelet count ( 32888494) Rosacea symptom severity ( 29771307) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494)
Interacting Genes		11 interacting genes: C22orf39 EML2 GRXCR1 MNS1 NME7 SNX1 SNX2 SPANXB1 TEX11 TFIP11 TSG101	48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35
Entrez ID		254122	6642
HPRD ID		08090	03171
Ensembl ID		ENSG00000172803	ENSG00000028528
Uniprot IDs		Q86XE0	Q13596
PDB IDs		6E8R	2I4K 4FZS
Enriched GO Terms of Interacting Partners?
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