FSCN1 and DNAJB9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FSCN1	DNAJB9
Description		fascin actin-bundling protein 1	DnaJ heat shock protein family (Hsp40) member B9
Image
GO Annotations	Cellular Component	Stress Fiber Ruffle Podosome Cytoplasm Cytosol Cytoskeleton Microvillus Cell-cell Junction Cell Cortex Actin Cytoskeleton Lamellipodium Filopodium Growth Cone Cell Projection Membrane Microspike Extracellular Exosome	Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	RNA Binding Actin Binding Protein Binding Protein-macromolecule Adaptor Activity Cadherin Binding Actin Filament Binding	Protein Binding Hsp70 Protein Binding Chaperone Binding Misfolded Protein Binding
	Biological Process	Cell-cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Lamellipodium Assembly Cell Migration Microspike Assembly Actin Cytoskeleton Organization Parallel Actin Filament Bundle Assembly Regulation Of Microvillus Assembly Regulation Of Actin Cytoskeleton Organization Establishment Of Apical/basal Cell Polarity Cell Motility Actin Filament Bundle Assembly Positive Regulation Of Filopodium Assembly Positive Regulation Of Podosome Assembly Positive Regulation Of Extracellular Matrix Disassembly	Positive Regulation Of Immunoglobulin Production Response To Unfolded Protein B Cell Differentiation Ubiquitin-dependent ERAD Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of IRE1-mediated Unfolded Protein Response
Pathways		Interleukin-4 and Interleukin-13 signaling	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Metabolite levels ( 23823483) Smoking behavior ( 22006218)
Interacting Genes		14 interacting genes: ACTA1 ACTC1 CTNNB1 DNAJB9 MAD1L1 MAPK8IP2 MYCBP2 NGFR OXTR PRKCA PRKCD RAB1A SMURF1 YWHAQ	10 interacting genes: DYNLL1 ECPAS FAM71C FSCN1 MYL6 PLK1 RFK SLC16A8 TCEA2 TCERG1
Entrez ID		6624	4189
HPRD ID		04068	07047
Ensembl ID		ENSG00000075618	ENSG00000128590
Uniprot IDs		A0A384MEG1 B3KTA3 Q16658	Q6FIF1 Q9UBS3
PDB IDs		1DFC 3LLP 3P53 4GOV 4GOY 4GP0 4GP3 6B0T 6I0Z 6I10 6I11 6I12 6I13 6I14 6I15 6I16 6I17 6I18	2CTR
Enriched GO Terms of Interacting Partners?
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