FSCN1 and MYCBP2

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		FSCN1	MYCBP2
Description		fascin actin-bundling protein 1	MYC binding protein 2
Image
GO Annotations	Cellular Component	Stress Fiber Ruffle Podosome Cytoplasm Cytosol Cytoskeleton Microvillus Cell-cell Junction Cell Cortex Actin Cytoskeleton Lamellipodium Filopodium Growth Cone Cell Projection Membrane Microspike Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Actin Binding Protein Binding Protein-macromolecule Adaptor Activity Cadherin Binding Actin Filament Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell-cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Lamellipodium Assembly Cell Migration Microspike Assembly Actin Cytoskeleton Organization Parallel Actin Filament Bundle Assembly Regulation Of Microvillus Assembly Regulation Of Actin Cytoskeleton Organization Establishment Of Apical/basal Cell Polarity Cell Motility Actin Filament Bundle Assembly Positive Regulation Of Filopodium Assembly Positive Regulation Of Podosome Assembly Positive Regulation Of Extracellular Matrix Disassembly	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance
Pathways		Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS			Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		14 interacting genes: ACTA1 ACTC1 CTNNB1 DNAJB9 MAD1L1 MAPK8IP2 MYCBP2 NGFR OXTR PRKCA PRKCD RAB1A SMURF1 YWHAQ	52 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 ATP1B3 CALM1 CD81 CDC14B CFL1 COMMD6 CUEDC2 DACH1 DHRS4L2 EDNRB ERBB3 FBXL3 FBXO45 FHL3 FSCN1 HSP90AB1 IGFBP6 LDHB LSM14A MAST3 MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 SCEL SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ
Entrez ID		6624	23077
HPRD ID		04068	10104
Ensembl ID		ENSG00000075618	ENSG00000005810
Uniprot IDs		A0A384MEG1 B3KTA3 Q16658	O75592
PDB IDs		1DFC 3LLP 3P53 4GOV 4GOY 4GP0 4GP3 6B0T 6I0Z 6I10 6I11 6I12 6I13 6I14 6I15 6I16 6I17 6I18	5O6C 6T7F
Enriched GO Terms of Interacting Partners?
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