SMN2 and CHTOP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMN2	CHTOP
Description		survival of motor neuron 2, centromeric	chromatin target of PRMT1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Nuclear Body Z Disc Axon SMN Complex SMN-Sm Protein Complex Cytoplasmic Ribonucleoprotein Granule Neuron Projection Perikaryon Gemini Of Coiled Bodies	Transcription Export Complex Nucleus Nucleoplasm Nucleolus Nuclear Speck Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	RNA Binding MRNA Binding Protein Binding Methyl-CpG Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly DNA-templated Transcription, Termination Nervous System Development	In Utero Embryonic Development MRNA Export From Nucleus Positive Regulation Of Cell Population Proliferation Positive Regulation Of Histone Methylation Positive Regulation Of ATPase Activity Positive Regulation Of Helicase Activity
Pathways		snRNP Assembly	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Nusinersen
Diseases
GWAS
Interacting Genes		37 interacting genes: BLOC1S6 BYSL CHTOP DDX20 DHX9 EHHADH FAM9B FBL FNDC11 GAR1 GEMIN2 HNRNPUL1 IQUB KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP6-1 KRTAP6-2 MAGED1 MBD2 POLR1C POLR2A PPIG SMN1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNU13 SPANXN2 TIAL1 USP9X VPS28	14 interacting genes: APOBEC3C APP DDX39A DDX39B ERH GSK3A KHDRBS2 PHLDB3 RBM3 SMN1 SMN2 SNRPA SRPK2 UBAP2L
Entrez ID		6607	26097
HPRD ID		09036	13163
Ensembl ID		ENSG00000205571	ENSG00000160679
Uniprot IDs		B4DP61 E7EQZ4 Q16637	A0A087X1B7 Q9Y3Y2
PDB IDs		1G5V 1MHN 2LEH 4A4E 4A4G 4GLI 4QQ6 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
Enriched GO Terms of Interacting Partners?
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