SMN2 and FBL

Number of citations of the paper that reports this interaction (PubMedID 8670859)
231

Data Source:
HPRD (in vivo, in vitro)

		SMN2	FBL
Description		survival of motor neuron 2, centromeric	fibrillarin
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Nuclear Body Z Disc Axon SMN Complex SMN-Sm Protein Complex Cytoplasmic Ribonucleoprotein Granule Neuron Projection Perikaryon Gemini Of Coiled Bodies	Fibrillar Center Dense Fibrillar Component Granular Component Nucleus Nucleoplasm Chromosome Nucleolus Cajal Body Membrane Box C/D RNP Complex Small-subunit Processome Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	TFIID-class Transcription Factor Complex Binding RNA Binding Protein Binding RRNA Methyltransferase Activity ATPase Binding Histone-glutamine Methyltransferase Activity
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly DNA-templated Transcription, Termination Nervous System Development	Box C/D RNA 3'-end Processing Osteoblast Differentiation RRNA Processing RRNA Methylation SnoRNA Localization Histone Glutamine Methylation
Pathways		snRNP Assembly	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		Nusinersen
Diseases
GWAS
Interacting Genes		37 interacting genes: BLOC1S6 BYSL CHTOP DDX20 DHX9 EHHADH FAM9B FBL FNDC11 GAR1 GEMIN2 HNRNPUL1 IQUB KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP6-1 KRTAP6-2 MAGED1 MBD2 POLR1C POLR2A PPIG SMN1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNU13 SPANXN2 TIAL1 USP9X VPS28	21 interacting genes: DDX17 DDX5 ERG H2AC20 KLF6 MAP3K14 PIN4 PRMT1 PRMT3 PRMT6 PRMT8 PSMB6 PTEN RUVBL1 RUVBL2 SMN1 SMN2 SNRPN TAF9 TBC1D17 ZNF792
Entrez ID		6607	2091
HPRD ID		09036	00617
Ensembl ID		ENSG00000205571	ENSG00000105202
Uniprot IDs		B4DP61 E7EQZ4 Q16637	P22087
PDB IDs		1G5V 1MHN 2LEH 4A4E 4A4G 4GLI 4QQ6 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU	2IPX
Enriched GO Terms of Interacting Partners?
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