UPF3A and IFITM2

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		UPF3A	IFITM2
Description		UPF3A regulator of nonsense mediated mRNA decay	interferon induced transmembrane protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Exon-exon Junction Complex Intracellular Membrane-bounded Organelle	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Protein-containing Complex
	Molecular Function	RNA Binding Protein Binding Structural Constituent Of Nuclear Pore Telomeric DNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleocytoplasmic Transport Positive Regulation Of Translation MRNA Transport	Immune Response Response To Virus Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Cellular Response To Interferon-beta Negative Regulation Of Viral Genome Replication Negative Regulation Of Viral Entry Into Host Cell Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Nodular sclerosis Hodgkin lymphoma ( 29196614) Pulse pressure ( 30578418)	Autoimmune thyroid disease ( 32581359) Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494 27863252) Mean platelet volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Myocardial infarction ( 33532862) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		10 interacting genes: ALYREF APP ERBB2 GSK3B IFITM2 NXF1 PIGT RBM8A SMG1 UPF1	4 interacting genes: KRTAP1-1 PTCD3 SLC10A1 UPF3A
Entrez ID		65110	10581
HPRD ID		09274	05718
Ensembl ID		ENSG00000169062	ENSG00000185201
Uniprot IDs		B3KUE7 Q9H1J1	Q01629
PDB IDs		2L08
Enriched GO Terms of Interacting Partners?
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