IFITM2 and UPF3A

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		IFITM2	UPF3A
Description		interferon induced transmembrane protein 2	UPF3A regulator of nonsense mediated mRNA decay
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Protein-containing Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Exon-exon Junction Complex Intracellular Membrane-bounded Organelle
	Molecular Function		RNA Binding Protein Binding Structural Constituent Of Nuclear Pore Telomeric DNA Binding
	Biological Process	Immune Response Response To Virus Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Cellular Response To Interferon-beta Negative Regulation Of Viral Genome Replication Negative Regulation Of Viral Entry Into Host Cell Defense Response To Virus Type I Interferon Signaling Pathway	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleocytoplasmic Transport Positive Regulation Of Translation MRNA Transport
Pathways		Interferon alpha/beta signaling	Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494 27863252) Mean platelet volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Myocardial infarction ( 33532862) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)	Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Nodular sclerosis Hodgkin lymphoma ( 29196614) Pulse pressure ( 30578418)
Interacting Genes		4 interacting genes: KRTAP1-1 PTCD3 SLC10A1 UPF3A	10 interacting genes: ALYREF APP ERBB2 GSK3B IFITM2 NXF1 PIGT RBM8A SMG1 UPF1
Entrez ID		10581	65110
HPRD ID		05718	09274
Ensembl ID		ENSG00000185201	ENSG00000169062
Uniprot IDs		Q01629	B3KUE7 Q9H1J1
PDB IDs			2L08
Enriched GO Terms of Interacting Partners?
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