DEPTOR and ANKRD11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DEPTOR	ANKRD11
Description		DEP domain containing MTOR interacting protein	ankyrin repeat domain 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of TOR Signaling Intracellular Signal Transduction Negative Regulation Of Cell Size Negative Regulation Of TORC2 Signaling Negative Regulation Of TORC1 Signaling Regulation Of Extrinsic Apoptotic Signaling Pathway	Anatomical Structure Morphogenesis Odontogenesis Of Dentin-containing Tooth Skeletal System Morphogenesis Face Morphogenesis
Pathways
Drugs
Diseases
GWAS		Body shape index ( 34021172) Choroid plexus volume ( 31530798) Depressive and manic episodes in bipolar disorder ( 26297903) Depressive episodes in bipolar disorder ( 26297903) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549) Idiopathic pulmonary fibrosis ( 31710517) Platelet count ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 33230300) Reticulocyte fraction of red cells ( 32888494)	Eosinophil counts ( 32888494) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Lymphocyte counts ( 32888494 27863252) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		13 interacting genes: ANKRD11 APP BTRC CCDC110 CHKA CUL5 FBXO25 LNX1 PSME3 RPS6KA1 RPS6KB1 TRAF1 TRIM41	93 interacting genes: ABHD11 AGR2 ANKRD33 ARID3A ARID5A BHLHB9 BRCC3 C10orf82 C11orf1 C18orf54 C1QTNF2 CALCA CCDC196 CCHCR1 CCN3 CDC23 CDCA7L CDR2L CEP44 COG4 DEPTOR FAM136A FAM221B FOLR3 FTO GOLGA2 GOLGA6L9 GRIPAP1 HAUS3 HDAC3 HDAC4 HDAC5 HOMEZ HOOK2 HRAS IGFBP6 IKZF1 ITGB3BP KANK2 KPNA3 KPNA6 KRT34 LZTS2 MKRN3 MTFR1L MTUS2 MXRA8 MYF5 NAB2 NCOA1 NCOA2 NCOA3 NOTO NTAQ1 PDE4DIP PIH1D2 PLAGL2 PPARA RAC3 RCOR3 RINT1 RPH3AL RSPO4 RUBCN SERTAD3 SNRNP35 SPANXN2 SPATA2 SPRY1 SRC STMN3 STRA8 SYTL3 TADA2B TFIP11 TLE5 TNNI1 TRAF2 TRIM37 TRIM54 TSPOAP1 TTC23L TXN UFC1 USH1G USP54 USP6 VDR ZNF426 ZNF552 ZNF655 ZNF688 ZRANB1
Entrez ID		64798	29123
HPRD ID		13137	12456
Ensembl ID		ENSG00000155792	ENSG00000167522
Uniprot IDs		Q8TB45	Q6UB99
PDB IDs
Enriched GO Terms of Interacting Partners?
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