CRTC3 and TICRR

		CRTC3	TICRR
Description		CREB regulated transcription coactivator 3	TOPBP1 interacting checkpoint and replication regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding CAMP Response Element Binding Protein Binding	Chromatin Binding Protein Binding
	Biological Process	Positive Regulation Of CREB Transcription Factor Activity Macrophage Activation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Energy Homeostasis	DNA Replication DNA Repair Mitotic G2 DNA Damage Checkpoint Signaling Response To Ionizing Radiation Regulation Of DNA-dependent DNA Replication Initiation Mitotic DNA Replication Checkpoint Signaling
Pathways		Transcriptional activation of mitochondrial biogenesis Circadian Clock Heme signaling
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 28067908 23128233) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)	Mean corpuscular hemoglobin ( 32888494) Resting oxygen saturation in chronic osbtructive pulmonary disease (pulse oxymetry) ( 24825563) Type 2 diabetes ( 31049640)
Interacting Genes		12 interacting genes: AEN C15orf32 CA13 HAPLN3 KLHL12 RCCD1 RGMA SIK2 TICRR UNC45A WDR93 YWHAG	3 interacting genes: APP CRTC3 TOPBP1
Entrez ID		64784	90381
HPRD ID		13384	11357
Ensembl ID		ENSG00000140577	ENSG00000140534
Uniprot IDs		Q6UUV7 Q8TEF4	Q7Z2Z1
PDB IDs
Enriched GO Terms of Interacting Partners?
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