CRTC3 and CA13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CRTC3	CA13
Description		CREB regulated transcription coactivator 3	carbonic anhydrase 13
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Cytosol Myelin Sheath Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding CAMP Response Element Binding Protein Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity
	Biological Process	Positive Regulation Of CREB Transcription Factor Activity Macrophage Activation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Energy Homeostasis	One-carbon Metabolic Process
Pathways		Transcriptional activation of mitochondrial biogenesis Circadian Clock Heme signaling	Reversible hydration of carbon dioxide
Drugs			Benzthiazide Cyclothiazide Zonisamide N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 28067908 23128233) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)	Blood protein levels ( 30072576 28240269) Blood trace element (Zn levels) ( 23720494)
Interacting Genes		12 interacting genes: AEN C15orf32 CA13 HAPLN3 KLHL12 RCCD1 RGMA SIK2 TICRR UNC45A WDR93 YWHAG	2 interacting genes: CRACR2B CRTC3
Entrez ID		64784	377677
HPRD ID		13384	12992
Ensembl ID		ENSG00000140577	ENSG00000185015
Uniprot IDs		Q6UUV7 Q8TEF4	Q8N1Q1
PDB IDs			3CZV 3D0N 3DA2 4HU1 4KNM 4KNN 4QIZ 4QJP 4QJX 4QSJ 5E2N 5LLA 5LLN 5OGJ 5OHH 6G5U
Enriched GO Terms of Interacting Partners?
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