FNDC3B and ADGRF5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FNDC3B	ADGRF5
Description		fibronectin type III domain containing 3B	adhesion G protein-coupled receptor F5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Vesicle Apical Part Of Cell
	Molecular Function	RNA Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process		Glomerular Filtration Energy Reserve Metabolic Process Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Glucose Homeostasis Negative Regulation Of Macrophage Activation Surfactant Homeostasis Fat Cell Differentiation Erythrocyte Development Pharyngeal Arch Artery Morphogenesis Positive Regulation Of Phospholipid Biosynthetic Process
Pathways			Surfactant metabolism
Drugs
Diseases
GWAS		Bell's palsy ( 33602968) Central corneal thickness ( 32528159 31798171 29760442 30894546) Corneal hysteresis ( 30894546) Corneal resistance factor ( 31246245 30894546) Corneal structure ( 23291589) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma (primary open-angle) ( 33627673) Glycated hemoglobin levels ( 34059833 28898252) Heart rate ( 23583979) Height ( 28552196 25282103 25429064 23563607 31562340 33713608) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Hypertrophic cardiomyopathy ( 33495596 33495597) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998 25173106 31798171 29785010 30054594 28073927 29235454) Intraocular pressure (Goldman correlated) ( 30894546) Keratoconus ( 33649486) Mean corpuscular hemoglobin ( 32888494) Myocardial infarction ( 33532862) Parkinson's disease ( 26227905) PR interval ( 32439900) Pulse pressure ( 30224653) Red cell distribution width ( 32888494 27863252 28957414) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triptolide cytotoxicity ( 26121980) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172 25673412 28448500) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood protein levels ( 30072576) Waist-hip ratio ( 28552196)
Interacting Genes		52 interacting genes: ABHD11 ABHD8 ADGRF5 BBS2 BICRAL BRWD1 C10orf55 C10orf82 C19orf54 C22orf15 CAMK2D CAPN3 CEMP1 DAPL1 DUSP10 ERCC6 GAS2L3 HAPLN2 KLHDC7B KRTAP11-1 L3MBTL3 MBD3L1 MCCD1 MVP NDUFAB1 PIK3R4 POGZ POU6F2 PRKAA2 REL RUSC1 SPSB2 SRARP STPG4 SUOX TEKT5 TEPSIN TESMIN TEX43 TEX48 TIAM1 TOX4 TRAF2 TRIM35 TRIM42 TRIP13 TTN UBAP2 USP54 VAC14 YPEL3 ZMYND19	4 interacting genes: CABP2 FNDC3B NFYC SEC13
Entrez ID		64778	221395
HPRD ID		10943	11010
Ensembl ID		ENSG00000075420	ENSG00000069122
Uniprot IDs		Q53EP0	Q8IZF2
PDB IDs
Enriched GO Terms of Interacting Partners?
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