SMYD3 and SCCPDH

		SMYD3	SCCPDH
Description		SET and MYND domain containing 3	saccharopine dehydrogenase (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Extracellular Region Nucleus Mitochondrion Lipid Droplet Plasma Membrane Membrane Midbody Platelet Alpha Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Complex Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding	Oxidoreductase Activity
	Biological Process	Nucleosome Assembly Negative Regulation Of Protein Kinase Activity Myotube Cell Development Positive Regulation Of Peptidyl-serine Phosphorylation Histone Lysine Methylation Establishment Of Protein Localization Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dexamethasone Stimulus	Glycolipid Biosynthetic Process
Pathways		PKMTs methylate histone lysines	Platelet degranulation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Blood metabolite levels ( 26401656) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fractional exhaled nitric oxide (childhood) ( 24315451) Gut microbiota relative abundance (Bifidobacterium) ( 33208821) Malaria ( 31844061) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) PR interval ( 32439900) Renal underexcretion gout ( 32238385) Response to serotonin reuptake inhibitors in non-psychotic unipolar depression ( 26348319) Systemic lupus erythematosus ( 29848360) Upper eyelid sagging severity ( 24869959)	Apolipoprotein B levels ( 32203549) Metabolite levels ( 23823483)
Interacting Genes		22 interacting genes: APP CAMK2B CSTF2T CYP39A1 EED EZH2 H3-4 H3-5 HELZ HSP90AA1 MKRN3 NDUFAB1 NFYB NUP54 PBX2 PKN1 POLR2K SCCPDH SHC3 TRIT1 VANGL1 ZNF557	4 interacting genes: DESI2 PAXIP1 SMYD3 ZNF669
Entrez ID		64754	51097
HPRD ID		12297	13038
Ensembl ID		ENSG00000185420	ENSG00000143653
Uniprot IDs		B3KN46 Q9H7B4	A0A384NPM7 Q8NBX0
PDB IDs		3MEK 3OXF 3OXG 3OXL 3PDN 3QWP 3RU0 5CCL 5CCM 5EX0 5EX3 5HI7 5HQ8 5V37 5XXD 5XXG 5XXJ 5YJO 6IJL 6O9O 6P6G 6P6K 6P7Z 6PAF 6YUH 7BJ1
Enriched GO Terms of Interacting Partners?
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