MTMR14 and LTK

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		MTMR14	LTK
Description		myotubularin related protein 14	leukocyte receptor tyrosine kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Cytosol Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Membrane Receptor Complex
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity	Protein Kinase Activity Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Macroautophagy Peptidyl-tyrosine Dephosphorylation	Protein Phosphorylation Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Cell Population Proliferation Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Neuron Projection Development Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Regulation Of Neuron Differentiation Cellular Response To Retinoic Acid
Pathways		Macroautophagy Synthesis of PIPs at the plasma membrane
Drugs			Fostamatinib
Diseases
GWAS		Daytime sleep phenotypes ( 27126917)	High density lipoprotein cholesterol levels ( 31928498) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Lymphocyte percentage of white cells ( 32888494) Type 2 diabetes ( 30297969) Urinary albumin excretion (no hypertensive medication) ( 30220432)
Interacting Genes		9 interacting genes: APP ENO3 EPHA1 EPHA7 EPHB2 LTK OXNAD1 TIE1 TP53BP2	6 interacting genes: CBL DUSP6 MTMR14 PIK3C2B PTPN1 SHC1
Entrez ID		64419	4058
HPRD ID		08654	01052
Ensembl ID		ENSG00000163719	ENSG00000062524
Uniprot IDs		Q8NCE2 Q8WYY9	P29376
PDB IDs
Enriched GO Terms of Interacting Partners?
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