IKZF4 and MOB1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IKZF4	MOB1A
Description		IKAROS family zinc finger 4	MOB kinase activator 1A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Protein-containing Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization	Positive Regulation Of Protein Phosphorylation Signal Transduction Hippo Signaling
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Alopecia areata ( 20596022 25608926) Anorexia nervosa ( 28494655) Asthma ( 21804548 31959851 32700739 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autoimmune traits (pleiotropy) ( 30572963) Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Cognitive function ( 25644384) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil percentage of granulocytes ( 27863252) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Type 1 diabetes ( 21829393 25751624 18198356) Vitiligo ( 27723757 22561518)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		20 interacting genes: CDC7 CHD4 CSNK1D FHL2 FOXP3 HDAC2 IKZF1 IKZF2 IKZF3 IKZF5 MCRS1 MOB1A MOB3C NFKBIA NRG1 SIN3A SIN3B TCAF1 TCEA2 TXK	21 interacting genes: APP CCDC85B CDK2 CMTM3 FAM118A FAM9B GMEB2 IKZF4 KANK2 KXD1 LZTFL1 MST1 PCYT1A PJA2 PTPN5 SEPTIN3 STRN3 TDO2 TMEM190 TRIM32 WASHC3
Entrez ID		64375	55233
HPRD ID		05874	14727
Ensembl ID		ENSG00000123411	ENSG00000114978
Uniprot IDs		Q9H2S9	Q9H8S9
PDB IDs		2MA7	1PI1 4J1V 4JIZ 5BRK 5BRM 5TWF 5TWG 5TWH 5XQZ 6MCP 6MCQ
Enriched GO Terms of Interacting Partners?
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