TMEM253 and RAPGEF5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

		TMEM253	RAPGEF5
Description		transmembrane protein 253	Rap guanine nucleotide exchange factor 5
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Nucleoplasm Nuclear Body
	Molecular Function		Guanyl-nucleotide Exchange Factor Activity GTP-dependent Protein Binding
	Biological Process		Small GTPase Mediated Signal Transduction Nervous System Development Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS			Asthma ( 34103634) Cutaneous malignant melanoma ( 32341527) Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Diastolic blood pressure ( 30224653) Gamma glutamyl transferase levels ( 33339817) Glaucoma ( 30104761) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Night sleep phenotypes ( 27126917) Spatial processing ( 31596458) Squamous cell lung carcinoma ( 28604730) Thyroid stimulating hormone levels ( 17903292) Urinary albumin excretion ( 32277301)
Interacting Genes		2 interacting genes: RAPGEF5 TUBA1B	8 interacting genes: ITGB8 MRAS PLAC9 RAP1A RAP2A RAP2B TMEM253 VANGL1
Entrez ID		643382	9771
HPRD ID			15208
Ensembl ID		ENSG00000232070	ENSG00000136237
Uniprot IDs		P0C7T8	A8MQ07 Q5JPD2 Q92565
PDB IDs			1WGY
Enriched GO Terms of Interacting Partners?
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