SEMG2 and SERPINA5

Number of citations of the paper that reports this interaction (PubMedID 8665956)
10

Data Source:
HPRD (in vitro)

		SEMG2	SERPINA5
Description		semenogelin 2	serpin family A member 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Extracellular Exosome	Acrosomal Membrane Extracellular Region Extracellular Space External Side Of Plasma Membrane Membrane Platelet Alpha Granule Platelet Dense Tubular Network Protein-containing Complex Protein C Inhibitor-TMPRSS7 Complex Protein C Inhibitor-TMPRSS11E Complex Protein C Inhibitor-PLAT Complex Protein C Inhibitor-PLAU Complex Protein C Inhibitor-thrombin Complex Protein C Inhibitor-KLK3 Complex Protein C Inhibitor-plasma Kallikrein Complex Collagen-containing Extracellular Matrix Extracellular Exosome Protein C Inhibitor-coagulation Factor V Complex Protein C Inhibitor-coagulation Factor Xa Complex Protein C Inhibitor-coagulation Factor XI Complex
	Molecular Function	Protease Binding Protein Binding Zinc Ion Binding	Retinoic Acid Binding Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Glycosaminoglycan Binding Heparin Binding Phosphatidylcholine Binding Acrosin Binding
	Biological Process	Antibacterial Humoral Response Sperm Capacitation Coagulation Positive Regulation Of Serine-type Endopeptidase Activity Negative Regulation Of Flagellated Sperm Motility	Lipid Transport Spermatogenesis Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Negative Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Seminal Vesicle Development
Pathways			Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation
Drugs		Zinc chloride Zinc sulfate, unspecified form	Urokinase Drotrecogin alfa Tifuvirtide PPL-100
Diseases
GWAS		Asthma ( 29273806) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Malaria ( 31844061)	Blood protein levels ( 30072576 29875488 28240269) Serum albumin level ( 29403010) Serum total protein level ( 29403010)
Interacting Genes		8 interacting genes: KLK2 KLK3 PRKAR2A PRKCA PTPRF SEMG1 SERPINA5 TGM1	23 interacting genes: ACR CBL COPS6 EPS8 F10 F11 F2 FBLN5 FGA FGB FGG KLK1 KLK2 KLK3 KLKB1 PIAS4 PLAT PLAU PROC RCHY1 RIDA SEMG2 THBD
Entrez ID		6407	5104
HPRD ID		01642	03503
Ensembl ID		ENSG00000124157	ENSG00000188488
Uniprot IDs		Q02383	A0A024R6N9 B4DDH1 P05154
PDB IDs			1LQ8 1PAI 2HI9 2OL2 2PAI 3DY0
Enriched GO Terms of Interacting Partners?
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