SDC2 and PPP3CC

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SDC2	PPP3CC
Description		syndecan 2	protein phosphatase 3 catalytic subunit gamma
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Cell Surface Integral Component Of Membrane Lysosomal Lumen Collagen-containing Extracellular Matrix	Cytoplasm Cytosol Calcineurin Complex Presynapse Glutamatergic Synapse
	Molecular Function	Protein Binding PDZ Domain Binding Identical Protein Binding	Protein Binding Calmodulin Binding Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Biological_process Cell Migration Dendrite Morphogenesis Regulation Of Dendrite Morphogenesis	Protein Dephosphorylation Brain Development Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Synaptic Vesicle Endocytosis
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Cell surface interactions at the vascular wall Syndecan interactions Syndecan interactions Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) EPHB-mediated forward signaling Defective B3GALT6 causes EDSP2 and SEMDJL1 Post-translational protein phosphorylation Retinoid metabolism and transport	Activation of BAD and translocation to mitochondria DARPP-32 events
Drugs		Sargramostim
Diseases
GWAS		Post-traumatic stress disorder ( 26114229) Refractive error ( 32231278)	General risk tolerance (MTAG) ( 30643258) HIV-1 viral setpoint ( 20205591) Verbal declarative memory ( 25648963)
Interacting Genes		28 interacting genes: ANOS1 ASPH BAG6 CASK CSF2 CYP2C18 EPHB2 EZR FGF2 FN1 HGF ITGB4 LAMA3 NF1 PF4 PPP3CC PRKCA PRKCB PRKCG REG3A SDCBP SERPINA1 SERPINC1 SPARC TGFB1 TGFBR3 TNFSF13 TRAPPC4	19 interacting genes: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B ENTPD4 GFRA2 HAX1 ITPKC LEPROTL1 PPP3R1 SDC2 SLC18A1 SORBS3 SPATA33 TGFBR1 THAP7 UNC119
Entrez ID		6383	5533
HPRD ID		00803	00236
Ensembl ID		ENSG00000169439	ENSG00000120910
Uniprot IDs		A0A024R9D1 E9PBI9 P34741	P48454
PDB IDs		6ITH
Enriched GO Terms of Interacting Partners?
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