CXCL5 and ALPP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CXCL5	ALPP
Description		C-X-C motif chemokine ligand 5	alkaline phosphatase, placental
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane
	Molecular Function	Protein Binding Chemokine Activity Identical Protein Binding CXCR Chemokine Receptor Binding	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding
	Biological Process	Chemotaxis Inflammatory Response Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide	Dephosphorylation
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Intra-Golgi traffic
Drugs			Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		CXCL5 levels ( 25147954) Inflammatory bowel disease ( 23128233) Metabolite levels ( 22916037) Urate levels (BMI interaction) ( 25811787)	Blood protein levels ( 30072576) Height ( 19570815) Refractive error ( 32231278)
Interacting Genes		20 interacting genes: ACKR1 ACTN3 ALPP CCL11 CCL20 CXCL1 CXCL14 CXCL2 CXCL3 CXCR1 CXCR2 EFEMP2 FBLN1 GRN MEOX2 MGAT5B MMP9 NOTCH2NLA VWC2L XCL2	44 interacting genes: ADAMTSL4 ALPG CRCT1 CREB5 CXCL5 CYSRT1 FBXO34 GEMIN4 GPLD1 GSC2 HOXA1 IGFBP6 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP5-9 LATS1 LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE5A LELP1 MEOX2 MPHOSPH9 NBPF19 NLGN3 NOTCH2NLA NR4A3 OTX1 PIGK POU4F2 RGS19 RGS20 SMCP TGM1 TUBA4A
Entrez ID		6374	250
HPRD ID		08976	01379
Ensembl ID		ENSG00000163735	ENSG00000163283
Uniprot IDs		P42830 Q6I9S7	B2R7C7 P05187
PDB IDs		2MGS	1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2
Enriched GO Terms of Interacting Partners?
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