ALPP and CXCL5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ALPP	CXCL5
Description		alkaline phosphatase, placental	C-X-C motif chemokine ligand 5
Image
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane	Extracellular Region Extracellular Space
	Molecular Function	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding	Protein Binding Chemokine Activity Identical Protein Binding CXCR Chemokine Receptor Binding
	Biological Process	Dephosphorylation	Chemotaxis Inflammatory Response Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Intra-Golgi traffic	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 19570815) Refractive error ( 32231278)	CXCL5 levels ( 25147954) Inflammatory bowel disease ( 23128233) Metabolite levels ( 22916037) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		44 interacting genes: ADAMTSL4 ALPG CRCT1 CREB5 CXCL5 CYSRT1 FBXO34 GEMIN4 GPLD1 GSC2 HOXA1 IGFBP6 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP5-9 LATS1 LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE5A LELP1 MEOX2 MPHOSPH9 NBPF19 NLGN3 NOTCH2NLA NR4A3 OTX1 PIGK POU4F2 RGS19 RGS20 SMCP TGM1 TUBA4A	20 interacting genes: ACKR1 ACTN3 ALPP CCL11 CCL20 CXCL1 CXCL14 CXCL2 CXCL3 CXCR1 CXCR2 EFEMP2 FBLN1 GRN MEOX2 MGAT5B MMP9 NOTCH2NLA VWC2L XCL2
Entrez ID		250	6374
HPRD ID		01379	08976
Ensembl ID		ENSG00000163283	ENSG00000163735
Uniprot IDs		B2R7C7 P05187	P42830 Q6I9S7
PDB IDs		1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2	2MGS
Enriched GO Terms of Interacting Partners?
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