SCT and SCTR

Number of citations of the paper that reports this interaction (PubMedID 7782300)
32

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		SCT	SCTR
Description		secretin	secretin receptor
Image
GO Annotations	Cellular Component	Cellular_component Extracellular Region Extracellular Space	Cytoplasmic Microtubule Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Binding Signaling Receptor Binding Hormone Activity Protein Binding Digestive Hormone Activity Protein N-terminus Binding	G Protein-coupled Peptide Receptor Activity Secretin Receptor Activity Peptide Hormone Binding
	Biological Process	Diet Induced Thermogenesis Signal Transduction Brain Development Cellular Water Homeostasis Hippocampus Development Pancreatic Juice Secretion Response To Nutrient Levels Regulation Of Appetite Positive Regulation Of CAMP-mediated Signaling Regulation Of Synaptic Plasticity Embryonic Digestive Tract Development Positive Regulation Of Lipid Catabolic Process Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of Somatostatin Secretion Negative Regulation Of Gastrin-induced Gastric Acid Secretion	Diet Induced Thermogenesis Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Brain Development Cellular Water Homeostasis Response To Nutrient Levels Regulation Of Appetite Positive Regulation Of CAMP-mediated Signaling Regulation Of Synaptic Plasticity
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production	G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs			Secretin human
Diseases
GWAS			Bipolar disorder ( 31043756) Type 2 diabetes ( 32499647 30718926)
Interacting Genes		8 interacting genes: HGS HOXA1 MEIS2 MEP1A MEP1B SCTR USHBP1 VIPR1	9 interacting genes: ADCYAP1 CALM1 CPAMD8 CYFIP1 DNAL4 PRKAR2A PRKCA SCT SNTA1
Entrez ID		6343	6344
HPRD ID		08354	01628
Ensembl ID		ENSG00000070031	ENSG00000080293
Uniprot IDs		P09683	P47872 Q8IV17
PDB IDs		6WI9 6WZG 7D3S	6WI9 6WZG 7D3S
Enriched GO Terms of Interacting Partners?
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