SCT and MEIS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCT	MEIS2
Description		secretin	Meis homeobox 2
Image
GO Annotations	Cellular Component	Cellular_component Extracellular Region Extracellular Space	Chromatin Nucleus Perinuclear Region Of Cytoplasm
	Molecular Function	G Protein-coupled Receptor Binding Signaling Receptor Binding Hormone Activity Protein Binding Digestive Hormone Activity Protein N-terminus Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Diet Induced Thermogenesis Signal Transduction Brain Development Cellular Water Homeostasis Hippocampus Development Pancreatic Juice Secretion Response To Nutrient Levels Regulation Of Appetite Positive Regulation Of CAMP-mediated Signaling Regulation Of Synaptic Plasticity Embryonic Digestive Tract Development Positive Regulation Of Lipid Catabolic Process Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of Somatostatin Secretion Negative Regulation Of Gastrin-induced Gastric Acid Secretion	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS			Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		8 interacting genes: HGS HOXA1 MEIS2 MEP1A MEP1B SCTR USHBP1 VIPR1	50 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CHRNA7 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3
Entrez ID		6343	4212
HPRD ID		08354	03443
Ensembl ID		ENSG00000070031	ENSG00000134138
Uniprot IDs		P09683	A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770
PDB IDs		6WI9 6WZG 7D3S	3K2A 4XRM 5BNG 5EG0
Enriched GO Terms of Interacting Partners?
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