RPS27 and ENOPH1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RPS27	ENOPH1
Description		ribosomal protein S27	enolase-phosphatase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Ribosome Postsynaptic Density Cytosolic Ribosome Cytosolic Small Ribosomal Subunit	Nucleus Cytosol
	Molecular Function	DNA Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding	Magnesium Ion Binding Protein Binding 2,3-diketo-5-methylthiopentyl-1-phosphate Enolase Activity 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate Phosphatase Activity Acireductone Synthase Activity
	Biological Process	Ribosomal Small Subunit Assembly Cytoplasmic Translation RRNA Processing Translation	Dephosphorylation L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Major pathway of rRNA processing in the nucleolus and cytosol Mitotic Prometaphase Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency EML4 and NUDC in mitotic spindle formation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Methionine salvage pathway
Drugs			2-OXOHEPTYLPHOSPHONIC ACID
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		15 interacting genes: ACTN1 ACTN4 APC ENOPH1 ENTPD4 MARS1 NACAD NSG2 PPBP PSME3 PTEN RTN4 SKIL TOM1 WDCP	7 interacting genes: ERBB3 RAB10 RAB7A RNF41 RPS27 TSC22D2 ZNF280A
Entrez ID		6232	58478
HPRD ID		04744	17467
Ensembl ID		ENSG00000177954	ENSG00000145293
Uniprot IDs		P42677	D6RA00 Q9UHY7
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I	1YNS 1ZS9
Enriched GO Terms of Interacting Partners?
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