RPS6KB1 and USP11

  • Number of citations of the paper that reports this interaction (PubMedID 29483509)
  • 14
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study)

RPS6KB1

USP11

Description ribosomal protein S6 kinase B1 ubiquitin specific peptidase 11
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body shape index ( 34021172)
  • C-reactive protein levels ( 30388399)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic lymphocytic leukemia or multiple sclerosis ( 31407831)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 23128233)
  • Multiple sclerosis ( 21833088)
  • Obesity-related traits ( 23251661)
  • Triglycerides ( 30275531)
Interacting Genes 62 interacting genes: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B CYB5R3 DEPTOR DPPA4 EEF2K EIF3B EIF3F EIF4B EIF4EBP1 EP300 FBXO7 GDI2P1 GRIA1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MARK2 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 PIP4K2A POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RPS6 RPTOR SRC STK11 SYK TBK1 TERT TRAF4 URI1 USP11 XPO1 22 interacting genes: BMI1 BRCA2 CBX8 CDKN1A DECR2 EIF4B LIMS1 LLGL1 MBD3 MTA2 NONO PCGF2 PML RANBP9 RELB RNF2 RPS6KB1 SETDB1 SUMO2 TBL3 TP53 UBC
Entrez ID 6198 8237
HPRD ID 10202 02081
Ensembl ID ENSG00000108443 ENSG00000102226
Uniprot IDs P23443 B4DGK3 P51784
PDB IDs 3A60 3A61 3A62 3WE4 3WF5 3WF6 3WF7 3WF8 3WF9 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46 4RLO 4RLP 5WBH 5WBK 4MEL 5OK6
Enriched GO Terms of Interacting Partners?
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