ZNF704 and RECK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF704	RECK
Description		zinc finger protein 704	reversion inducing cysteine rich protein with kazal motifs
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Plasma Membrane Membrane Anchored Component Of Membrane Wnt Signalosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Wnt-protein Binding Coreceptor Activity Involved In Canonical Wnt Signaling Pathway
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Blood Vessel Maturation Sprouting Angiogenesis Embryo Implantation Extracellular Matrix Organization Negative Regulation Of Cell Migration Embryonic Forelimb Morphogenesis Regulation Of Angiogenesis Canonical Wnt Signaling Pathway Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Metalloendopeptidase Activity
Pathways		Generic Transcription Pathway	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Asthma ( 31959851) Blood urea nitrogen levels ( 31152163) Cannabis use ( 30150663) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Pre-treatment viral load in HIV-1 infection ( 31219150) Zinc levels ( 26025379)	Bipolar disorder (inflammation and infection response interaction) ( 25781172) IgG glycosylation ( 23382691)
Interacting Genes		1 interacting genes: RECK	44 interacting genes: ADAM12 BMF C22orf39 CCN3 CEP44 CFP CTH CTIF CYSRT1 DISC1 EFHC2 GLRX3 INCA1 KEAP1 KLHL20 KRT40 KRTAP10-8 KRTAP13-2 KRTAP26-1 KRTAP3-1 LCN1 MEOX2 MLPH MMP9 MTNR1B NBPF19 NDUFB7 NOTCH2NLA NR4A3 NUDT16L1 OXER1 PRIM2 REL RPS6KA1 SIGMAR1 SPSB2 SSC4D TCF4 TEKT4 TRIM39 TRIM69 USHBP1 ZNF438 ZNF704
Entrez ID		619279	8434
HPRD ID		18864	05567
Ensembl ID		ENSG00000164684	ENSG00000122707
Uniprot IDs		Q6ZNC4	A8K9D8 O95980 Q6P9E2
PDB IDs
Enriched GO Terms of Interacting Partners?
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