RECK and KRTAP13-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RECK	KRTAP13-2
Description		reversion inducing cysteine rich protein with kazal motifs	keratin associated protein 13-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Anchored Component Of Membrane Wnt Signalosome	Cytosol Intermediate Filament
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Wnt-protein Binding Coreceptor Activity Involved In Canonical Wnt Signaling Pathway	Protein Binding
	Biological Process	Blood Vessel Maturation Sprouting Angiogenesis Embryo Implantation Extracellular Matrix Organization Negative Regulation Of Cell Migration Embryonic Forelimb Morphogenesis Regulation Of Angiogenesis Canonical Wnt Signaling Pathway Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Metalloendopeptidase Activity
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Keratinization
Drugs
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172) IgG glycosylation ( 23382691)
Interacting Genes		44 interacting genes: ADAM12 BMF C22orf39 CCN3 CEP44 CFP CTH CTIF CYSRT1 DISC1 EFHC2 GLRX3 INCA1 KEAP1 KLHL20 KRT40 KRTAP10-8 KRTAP13-2 KRTAP26-1 KRTAP3-1 LCN1 MEOX2 MLPH MMP9 MTNR1B NBPF19 NDUFB7 NOTCH2NLA NR4A3 NUDT16L1 OXER1 PRIM2 REL RPS6KA1 SIGMAR1 SPSB2 SSC4D TCF4 TEKT4 TRIM39 TRIM69 USHBP1 ZNF438 ZNF704	80 interacting genes: ANAPC11 ANXA11 BCL6 C11orf1 C22orf39 CBFA2T2 CCDC125 CCDC24 CCDC57 CCNK CRYBA1 CSKMT CYSRT1 ENKD1 EPDR1 ETFDH FANCL FBXO17 FCHO1 GATA3 GEMIN4 GNE GPS2 GRN HNRNPH1 HOXA1 HR KCTD9 KLHL38 KPRP KRT3 KRTAP1-1 KRTAP10-5 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP4-4 KRTAP4-5 KRTAP9-2 MAGOHB MEOX2 MGAT5B NBPF19 NEK8 NHLRC4 NOTCH2NLA OIP5 OTX1 P4HB PATZ1 PHETA1 PITX1 POU2AF1 PPP1R32 RECK RHOXF2 SLC25A18 SLIT1 SMUG1 SNRPC SPEF1 SSC4D STK16 TCAF1 TEX37 TLE5 TNS2 TRAPPC6A TRIM68 TSPYL6 TSSK3 UNC5CL VGLL3 VWC2 YPEL3 ZIC1
Entrez ID		8434	337959
HPRD ID		05567	11201
Ensembl ID		ENSG00000122707	ENSG00000182816
Uniprot IDs		A8K9D8 O95980 Q6P9E2	Q52LG2
PDB IDs
Enriched GO Terms of Interacting Partners?
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