RPL37 and WIF1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		RPL37	WIF1
Description		ribosomal protein L37	WNT inhibitory factor 1
Image
GO Annotations	Cellular Component	Cytosol Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Synapse	Extracellular Region Cell Surface
	Molecular Function	RNA Binding Structural Constituent Of Ribosome RRNA Binding Metal Ion Binding MDM2/MDM4 Family Protein Binding Ubiquitin Ligase Inhibitor Activity	Signaling Receptor Binding Protein Binding Wnt-protein Binding
	Biological Process	Cytoplasmic Translation Translation Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity	Signal Transduction Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Fat Cell Differentiation Anatomical Structure Development
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	TCF dependent signaling in response to WNT Negative regulation of TCF-dependent signaling by WNT ligand antagonists
Drugs		(S)-3-phenyllactic acid PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE Virginiamycin S1 Anisomycin Puromycin
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Hippocampal fissure volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 22504421) Macular thickness ( 30535121) Post bronchodilator FEV1/FVC ratio ( 26634245) Subiculum volume ( 30279459) Total hippocampal volume ( 30279459)
Interacting Genes		6 interacting genes: APP POLR1B SQSTM1 SRPK2 TCF3 WIF1	9 interacting genes: AURKA CRADD CYSRT1 FGFR4 ICOS KRTAP10-3 KRTAP10-8 RB1CC1 RPL37
Entrez ID		6167	11197
HPRD ID		16047	05541
Ensembl ID		ENSG00000145592	ENSG00000156076
Uniprot IDs		P61927	Q9Y5W5
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP	2D3J 2YGN 2YGO 2YGP 2YGQ
Enriched GO Terms of Interacting Partners?
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